UniPep--a database for human N-linked glycosites: a resource for biomarker discovery.

TitleUniPep--a database for human N-linked glycosites: a resource for biomarker discovery.
Publication TypeJournal Article
Year of Publication2006
AuthorsZhang H, Loriaux P, Eng J, Campbell D, Keller A, Moss P, Bonneau R, Zhang N, Zhou Y, Wollscheid B, Cooke K, Yi EC, Lee H, Peskind ER, Zhang J, Smith RD, Aebersold R
JournalGenome Biol
Volume7
Issue8
PaginationR73
Date Published2006
ISSN1465-6914
KeywordsComputational Biology, Databases, Genetic, Genetic Markers, Glycopeptides, Humans, Mass Spectrometry
Abstract

There has been considerable recent interest in proteomic analyses of plasma for the purpose of discovering biomarkers. Profiling N-linked glycopeptides is a particularly promising method because the population of N-linked glycosites represents the proteomes of plasma, the cell surface, and secreted proteins at very low redundancy and provides a compelling link between the tissue and plasma proteomes. Here, we describe UniPep http://www.unipep.org--a database of human N-linked glycosites--as a resource for biomarker discovery.

DOI10.1186/gb-2006-7-8-R73
PubMed URLhttp://www.ncbi.nlm.nih.gov/pubmed/16901351?dopt=Abstract
PMCPMC1779586
Alternate JournalGenome Biol.
PubMed ID16901351