The model organism as a system: integrating 'omics' data sets.
|Title||The model organism as a system: integrating 'omics' data sets.|
|Publication Type||Journal Article|
|Year of Publication||2006|
|Authors||Joyce AR, Palsson BØ|
|Journal||Nat Rev Mol Cell Biol|
|Date Published||2006 Mar|
|Keywords||Animals, Cell Physiological Phenomena, DNA, Genome, Genomics, Models, Biological, Neural Networks (Computer), Proteins, Proteome, Transcription, Genetic|
Various technologies can be used to produce genome-scale, or 'omics', data sets that provide systems-level measurements for virtually all types of cellular components in a model organism. These data yield unprecedented views of the cellular inner workings. However, this abundance of information also presents many hurdles, the main one being the extraction of discernable biological meaning from multiple omics data sets. Nevertheless, researchers are rising to the challenge by using omics data integration to address fundamental biological questions that would increase our understanding of systems as a whole.
|Alternate Journal||Nat. Rev. Mol. Cell Biol.|